2021 Varsity Boys’ Lacrosse Schedule
| Day | Date | Opponent | Location | Time | Score |
| Thursday | March 25 | Gerstell | Gerstell | 4:00 pm | L, 5-13 |
| Wednesday | March 31 | FCA | CPS | 4:00 pm | L, 2-11 |
| Tuesday | April 6 | Indian Creek (scrimmage) |
Indian Creek | 4:30 pm | |
| Friday | April 9 | Jemicy | CPS | 4:00 pm | W, 6-5 |
| Thursday | April 15 | St. Johns CP | SJCP | 4:00 pm | L, 2-7 |
| Saturday | April 17 | St. Maria Goretti | CPS | 1:00 pm | |
| Tuesday | April 20 | Jemicy | Jemicy | 4:00 pm | W, 6-5 |
| Friday | April 23 | Key | CPS | 4:00 pm | L, 2-9 |
| Tuesday | April 27 | Pallotti | CPS | 3:30 pm | L, 9-15 |
| Friday | April 30 | Mt. Carmel | Mt. Carmel | 5:30 pm | W, 5-4 |
| Tuesday | May 5 | Chapelgate | CPS (Senior Game) |
4:00 pm | W, 18-3 |
| Thursday | May 6 | Beth Tifloh | Beth Tifloh | 4:30 pm | L, 2-10 |
| Friday | May 14 | MIAA Quarter-finals | Beth Tifloh | L, 8-10 |
